New Research Reveals Some Secrets Behind Ketamine’s Ability To Treat Depression

Ketamine, once used frequently as a battlefield anesthetic during wartime and more recently as a club drug, has found new acclaim in its use to treat depression. Scientists and medical professionals have documented Ketamine’s ability to alleviate depressive symptoms in just hours, but didn’t really understand how it worked. Now new research hints at revealing the secret mechanism of action. In the most recent study, mice were injected with a stress hormone and then recorded exhibiting depressive symptoms such as refusing to eat in addition to recording the loss of synaptic connections in their brain. The mice were then given a dose of ketamine as investigators recorded surprising brain changes. The synaptic connections previously recorded, started to repair themselves after only twelve hours. In addition to repaired neuronal connections, the depressive symptoms that the mice had shown disappeared almost instantly. Ketamine therapy holds great promise in being able to quickly treat suicidal thoughts and depression, and this research helps uncover its secrets.


I Don’t Need The Energy You Are Bringing To Me!


energy (Photo credit: Sean MacEntee)

The title of this post is a direct quote, made by me, to a well-meaning GI doctor. I am so proud of myself for being able to express this in a healthy, non confrontational way. Boy have I come a long way. Applause, applause. This got me thinking… many times during a day or week are we influenced by another person’s energy, for better or worse? And how aware are WE of the energy WE bring into each and every interaction?

For most of my life, I have been one of those odd people who are highly perceptive to energy. Only recently, though, have I begun to understand what this means exactly. As a survivor or abuse from before I could even read, I learned to read the moods of the people who surrounded me. I needed to, to survive. This coping mechanism might have been a brilliant way to stay alive when I was in an abusive situation, but as far as it working in day-to-day life….well, not so much. Like most coping skills we use when we are in midst of a crisis, they serve their purpose for that particular situation. It is when those same techniques are used when there is no real threat that we run the risk of negative consequences in a big way. Amazed that it took me this many decades to figure this out, but better late than never.

Throughout my life, I have been deeply affected by the moods of other people in my surroundings. If I was in a particularly good mood, coming home from work to a house filled with teenage chaos and angst could plunge my happy thoughts into the abyss and immediately I became mobilized into “fix it” mode.  When the man of my home would enter in a particularly gruff mood, I would quickly quiet the children, clean like a crazy person, and attempt to present a relaxing and calm environment for him. The result of all this? I was constantly on alert and always in response mode, never stopping along the way to just “be” or take even a moment for introspection. Decades of this instinctive reaction eventually wreaked havoc on both my physical health and my sanity.

Many years of hard work has allowed me this opportunity to reflect on my behavior patterns…..what ways they worked and the ways they destroyed. Although I appreciate my natural empathic abilities, I wish those abilities were inclusive of truly feeling MY feelings. It is a journey, my friends. So last week I had an appointment with a new gastroenterologist. After the obligatory weight and bp screening by the nurse, I sat in the exam room for 35 minutes waiting for the doctor. A recent trip to the ER for sudden dark rectal bleeding prompted me to follow-up with this new doctor. He entered the exam room and began to check my medical history along with the notes from my recent ER visit. Within seconds, his demeanor switched from calm and professional to extreme concern and a bit frantic. As he continued his review, I could literally feel the tension building in his body and caught myself instinctually reacting to that. When he began to state that he was going to call the short procedure unit at the hospital and get me on the schedule for an endoscopy and colonoscopy immediately, I had to stop him and change the dynamic in the room with my declaration above. He was more than a bit surprised by my statement, so I went on to explain that my body is very sensitive to mood and energy and that his anxiety was translating into my feelings of dizziness, light-headedness, increased pulse and heart rate,  shallow breathing…..none of which could be good for my long-term health. It also triggered a feeling of helplessness, doom and gloom, and hopelessness within me. Also not good things for my long-term health.

He excused himself from the exam room and returned a few minutes later, much calmer with a big smile on his face. He thanked me for my comment and said I was brave for voicing it. Me, brave. Go figure. It was his comment that has left me wondering just how often we are aware of the energy we bring to all our everyday interactions with each other. Of course it is difficult being present and conscious of this at every moment, but well worth the effort to try. Imagine the difference it would make in a child’s life and self image if, every time they entered our space, we lit up like Christmas morning and brought a loving, caring energy to our interactions with them. Imagine that. And for that reason alone, I for one am making a conscious effort to be aware of the energy I bring. How about you?

Yes, I'm a happy child.